摘要
目的:评价通博益脑胶囊(CTB)治疗高血压病的临床疗效。方法:选择高血压病患者200例,随机分为4组,分别服用CTB(0.6～1.5g,3/d),硝苯地平控释片(5mg～10mg,2/d)、卡托普利(12.5mg,25mg,3/d)及阿替洛尔(6.25mg～25mg,3/d),连续30d,每5d1次观察临床疗效、降压幅度和心率变化。结果:CTB组降压有效率为86.0%,略低于硝苯地平控释片组(90.0%)和卡托普利组(88.0%),高于阿替洛尔组(72.0%)。CTB组降压达到正常范围的时间迟于硝苯地平控释片和卡托普利组,早于阿替洛尔组,但无明显副作用。结论:通博益脑胶囊治疗高血压疗效确切,较硝苯地平控释片、卡托普利及阿替洛尔适用范围广。
Objective:To evaluate the curative effect of Tong Bo beneficial brain capuslae(CTB)on hypertension.Methods:200cases with hypertension were divided at random into 4 groups:CTB(in a dose of 0.6～1.5g,Tid),nifedipine controlled release tablet(in dose of 5～10mg,Bid),captopril(in a dose of 12.5mg,Bid～Tid)and atenolol(in a dose of 6.25～25mg,Tid),oral respectively;for successive 30 days.The curative effect,hypertension lowing range and change of heart rate were observed every 5days.Results:The total effective rate of CTB group was 86.0% and lower than of nifedipine group(90.0%)and captopril group(88.0%),but higher than that of atenolol group(72.0%).The recovery time of normal blood pressure in CTB group was later than that of nifedipine and captopril groups,but early than that of atenolol group.CTB has no remarkable side effects.Conclusion:CTB is effective for hypertension and has more wide spread application value than nifedipine,captopril and atenolol.
出处
《长沙医学院学报》
2005年第2期37-39,52,共4页
Journal of Changsha Medical University
关键词
通博益脑胶囊
高血压病
疗效
Tong Bo beneficial brain Capsulae(CTB)
Hypertension
treatment effect
