摘要
目的了解天津地区2017—2019年呼吸道感染住院患儿肺炎支原体(MP)感染的流行病学特点及分布情况,为MP的发生与流行提供理论依据。方法基于RNA恒温扩增技术,收集并分析天津地区2017—2019年9303例因呼吸道感染住院患儿的MP-RNA检测结果。结果2017—2019年天津地区因呼吸道感染住院患儿的MP-RNA检出率为32.46%(3020/9303),其中女性患儿的检出率为35.79%(1428/3990),男性患儿检出率为29.96%(1592/5313),男性患儿的MP-RNA检出率低于女性患儿,差异有统计学意义(χ^(2)=35.269,P<0.01);不同年龄段患儿的MP-RNA检出率差异有统计学意义(χ^(2)=1529.212,P<0.01),其中新生儿与婴儿组的患儿MP-RNA检出率最低为9.56%(259/2709),学龄前组的检出率最高为58.30%(1282/2199)。全年不同月份均可检出MP,其中9月的MP-RNA检出率最高为52.62%(462/878),不同月份之间的患儿MP-RNA检出率差异有统计学意义(χ^(2)=694.611,P<0.01)。MP感染有季节性差异,春、夏、秋、冬四季的MP-RNA检出率分别为16.96%(351/2069),34.08%(620/1819),47.47%(1332/2806)和27.48%(717/2609),不同季节的MP-RNA检出率差异有统计学意义(χ^(2)=546.606,P<0.01)。不同标本类型的检出率差异有统计学意义(χ^(2)=1029.283,P<0.01),其中肺泡灌洗液的MP-RNA检出率最高为72.34%(889/1229)。每月相对湿度和平均风速会影响MP-RNA检出率,风速越快、相对湿度越小,MP-RNA阳性检出率越低。结论天津地区2017—2019年9303例呼吸道感染住院患儿中,女性患儿MP-RNA检出率高于男性;随着年龄的增长,MP-RNA检出率越高;秋季为MP高发季节;肺泡灌洗液标本MP-RNA检出率明显高于其他标本类型;MP-RNA阳性检出率与风速、相对湿度的相关性明显。通过RNA恒温扩增技术能够初步掌握天津地区呼吸道感染住院患儿的MP流行病学特点,为临床防治MP感染提供一定参考。
Objective To understand the epidemiological characteristics and distribution of mycoplasma pneumoniae(MP)infection in hospitalized children with respiratory tract infection in Tianjin during 2017-2019,and to provide the scientific basis for the occurrence and prevalence of MP.Methods Based on RNA constant temperature amplification technology,MP-RNA test results of 9303 hospitalized children with respiratory tract infections in Tianjin during 2017-2019 were collected and analyzed.Results The detection rate of MP-RNA in hospitalized children with respiratory tract infections in Tianjin from 2017 to 2019 was 32.46%(3020/9303),with a detection rate of 35.79%(1428/3990)for female children and 29.96%(1592/5313)for male children.The detection rate of MP-RNA in children of different genders had statistical significance(P<0.01).The detection rate of MP-RNA in children of different age groups had statistical significance(P<0.01),with the lowest detection rate of MP-RNA in the neonatal and infant groups being 9.56%(259/2709),and the highest detection rate in the preschool group being 58.30%(1282/2199).MP could be detected in different months of the year,with the highest detection rate of MP-RNA in September being 52.62%(462/878).The detection rate of MP-RNA in children between different months was statistically significant(P<0.01).There were seasonal differences in MP infection,with the detection rates of MP-RNA in spring,summer,autumn,and winter being 16.96%(351/2069),34.08%(620/1819),47.47%(1332/2806),and 27.48%(717/2609),respectively.The detection rates of MP-RNA in different seasons were statistically significant(P<0.01).There were significant differences in detection rates among different specimen types(P<0.01),with the highest detection rate of MP-RNA in alveolar lavage fluid being 72.34%(889/1229).Monthly relative humidity and average wind speed could affect the MP-RNA detection rate.The faster the wind speed and the lower the relative humidity,the lower the MP-RNA positive detection rate.Conclusion Among 9303 hospit
作者
王露
马翠安
WANG Lu;MA Cui-an(Tianjin Pediatric Research Institute,Tianjin Children’s Hospital(Children’s Hospital of Tianjin University),Tianjin 300134,China;不详)
出处
《环境与健康杂志》
CAS
2024年第4期338-341,共4页
Journal of Environment and Health
基金
天津市卫生健康科技项目(TJWJ2022QN083)
天津市医学重点学科(专科)建设项目(TJYXZDXK-040A)
关键词
肺炎支原体
儿童
流行病学
气象因素
Mycoplasma pneumoniae
Children
Epidemiology
Meteorological factors
